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Target and Pathway |
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Target(s) |
Free fatty acid receptor 2 (FFAR2) |
Target Info
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Agonist |
[2] |
Free fatty acid receptor 3 (FFAR3) |
Target Info
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Agonist |
[3] |
References |
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REF 1 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1061).
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REF 2 |
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem. 2003 Mar 28;278(13):11312-9.
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REF 3 |
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):1045-50.
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