Drug Information
Target and Pathway | Top | |||
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Target(s) | Leucine-rich repeat kinase 2 (LRRK2) | Target Info | Inhibitor | [1] |
References | Top | |||
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REF 1 | Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J Med Chem. 2015 Jan 8;58(1):419-32. |
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