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| Target and Pathway |
Top |
| Target(s) |
Fibroblast growth factor receptor (FGFR) |
Target Info
|
Modulator |
[3] |
| Fibroblast growth factor receptor 1 (FGFR1) |
Target Info
|
Inhibitor |
[2] |
| Fibroblast growth factor receptor 2 (FGFR2) |
Target Info
|
Inhibitor |
[2] |
| Fibroblast growth factor receptor 3 (FGFR3) |
Target Info
|
Inhibitor |
[2] |
| References |
Top |
| REF 1 |
ClinicalTrials.gov (NCT03834220) Basket Trial in Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3- (FUZE Clinical Trial). U.S. National Institutes of Health.
|
| REF 2 |
Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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| REF 3 |
The fibroblast growth factor receptor genetic status as a potential predictor of the sensitivity to CH5183284/Debio 1347, a novel selective FGFR inhibitor. Mol Cancer Ther. 2014 Nov;13(11):2547-58.
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