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| Target and Pathway |
Top |
| Target(s) |
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) |
Target Info
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Inhibitor |
[2] |
| References |
Top |
| REF 1 |
Deubiquitylating enzymes and drug discovery: emerging opportunities. Nat Rev Drug Discov. 2018 Jan;17(1):57-78.
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| REF 2 |
Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1157-1170.
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