Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00EPS
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| Former ID |
DIB018047
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| Drug Name |
PMID18163548C4
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| Synonyms |
7IN; 1vja; AC1L9MNX; GTPL6545; BDBM50231520; US8476306, 6.12
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| Drug Type |
Small molecular drug
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| Indication | Myocardial ischemia [ICD-11: BA6Z; ICD-10: I20-I25] | Clinical trial | [1], [2] | |
| Reperfusion injury [ICD-11: ND56.Z] | Clinical trial | [1], [2] | ||
| Structure |
 |
Download2D MOL
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| Formula |
C21H27N5O6S
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| Canonical SMILES |
C1=CC=C(C=C1)CS(=O)(=O)NC(CO)C(=O)NC(CO)C(=O)NCC2=CC=C(C=C2)C(=N)N
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| InChI |
1S/C21H27N5O6S/c22-19(23)16-8-6-14(7-9-16)10-24-20(29)17(11-27)25-21(30)18(12-28)26-33(31,32)13-15-4-2-1-3-5-15/h1-9,17-18,26-28H,10-13H2,(H3,22,23)(H,24,29)(H,25,30)/t17-,18+/m0/s1
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| InChIKey |
ZNOKJHWJKULOGM-ZWKOTPCHSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Fragment-based discovery of mexiletine derivatives as orally bioavailable inhibitors of urokinase-type plasminogen activator. J Med Chem. 2008 Jan 24;51(2):183-6. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6545). | |||
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