Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00JQA
|
|||
| Drug Name |
Benzimidazole derivative 3
|
|||
| Synonyms |
PMID26815044-Compound-42
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Albinism [ICD-11: EC23.2; ICD-10: E70.3, H90.3] | Patented | [1] | |
| Ephelides [ICD-11: ED61.0] | Patented | [1] | ||
| Melasma [ICD-11: ED60.1] | Patented | [1] | ||
| Menkes disease [ICD-11: 5C64.0; ICD-10: E83.0] | Patented | [1] | ||
| Senile lentigines [ICD-11: ED61.0] | Patented | [1] | ||
| Structure |
 |
Download2D MOL |
||
| Formula |
C13H10N2O2
|
|||
| Canonical SMILES |
C1=CC=C2C(=C1)NC(=N2)C3=C(C=C(C=C3)O)O
|
|||
| InChI |
1S/C13H10N2O2/c16-8-5-6-9(12(17)7-8)13-14-10-3-1-2-4-11(10)15-13/h1-7,16-17H,(H,14,15)
|
|||
| InChIKey |
MTDSHRDWHUXPQH-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 63899-32-1
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Tyrosinase (TYR) | Target's Patent Info | [1] | |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Tyrosinase inhibitors: a patent review (2011-2015).Expert Opin Ther Pat. 2016;26(3):347-62. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.