Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00MJI
|
|||
| Drug Name |
Emactuzumab
|
|||
| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Phase 1 | [1] | |
| Company |
GenentechSouth San Francisco, CA
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Macrophage colony-stimulating factor 1 (CSF1) | Target Info | Antagonist | [1] |
| KEGG Pathway | Ras signaling pathway | |||
| Rap1 signaling pathway | ||||
| Cytokine-cytokine receptor interaction | ||||
| PI3K-Akt signaling pathway | ||||
| Osteoclast differentiation | ||||
| Hematopoietic cell lineage | ||||
| TNF signaling pathway | ||||
| Rheumatoid arthritis | ||||
| NetPath Pathway | TSH Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| EGFR1 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Signaling events mediated by PTP1B | |||
| Signaling events mediated by TCPTP | ||||
| Integrins in angiogenesis | ||||
| WikiPathways | Cytokines and Inflammatory Response | |||
| Hematopoietic Stem Cell Differentiation | ||||
| Differentiation Pathway | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| Folate Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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