Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00ONN
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| Drug Name |
Imidazo triazine derivative 1
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| Synonyms |
PMID27321640-Compound-64
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| Drug Type |
Small molecular drug
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| Company |
Pfizer Incorporated
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H18F3N7
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| Canonical SMILES |
CC1=NC(=C2N1N=CN=C2N(C)C)C3=C(N(N=C3)C)C4=CC=C(C=C4)C(F)(F)F
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| InChI |
1S/C19H18F3N7/c1-11-26-15(17-18(27(2)3)23-10-25-29(11)17)14-9-24-28(4)16(14)12-5-7-13(8-6-12)19(20,21)22/h5-10H,1-4H3
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| InChIKey |
UXZUQMRCSXERSI-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 2A (PDE2A) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Phosphodiesterase 2A (PDE2A) | Target's Patent Info | [1] | |
| KEGG Pathway | Purine metabolism | |||
| cGMP-PKG signaling pathway | ||||
| Morphine addiction | ||||
| NetPath Pathway | TSH Signaling Pathway | |||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Towards selective phosphodiesterase 2A (PDE2A) inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2016 Aug;26(8):933-46. | |||
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