Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D00PVH
|
|||
Drug Name |
Triazole derivative 2
|
|||
Synonyms |
PMID27724045-Compound-30
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Company |
Abbott
|
|||
Structure |
Download2D MOL |
|||
Formula |
C19H15Cl2N5S
|
|||
Canonical SMILES |
CC1=NN=C(N1C2=C(C(=CC=C2)Cl)Cl)NCC3=C(N=CC=C3)C4=CSC=C4
|
|||
InChI |
1S/C19H15Cl2N5S/c1-12-24-25-19(26(12)16-6-2-5-15(20)17(16)21)23-10-13-4-3-8-22-18(13)14-7-9-27-11-14/h2-9,11H,10H2,1H3,(H,23,25)
|
|||
InChIKey |
SMJNWZUHIGQMEW-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | P2X purinoceptor 7 (P2RX7) | Target Info | Antagonist | [1] |
Target's Patent Info | P2X purinoceptor 7 (P2RX7) | Target's Patent Info | [1] | |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Reactome | The NLRP3 inflammasome | |||
WikiPathways | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways |
References | Top | |||
---|---|---|---|---|
REF 1 | P2X7 receptor antagonists: a patent review (2010-2015).Expert Opin Ther Pat. 2017 Mar;27(3):257-267. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.