Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00QKS
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| Former ID |
DIB002727
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| Drug Name |
BMS-954561
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| Synonyms |
AGN-001; AGN-209323; AGN-2XXXXX; AGN-323; EHT-001; EHT/AGN-0001; EHT/AGN-001; GABA/nicotinic modulator (neuroscience), BMS; Neuropathic pain therapy, ExonHit/Allergan/Bristol-Myers Squibb
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| Indication | Diabetic neuropathy [ICD-11: 8C0Z; ICD-10: G63, G63.2] | Phase 2 | [1] | |
| Company |
Exonhit
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nicotinic acetylcholine receptor (nAChR) | Target Info | Modulator | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Highly sodium permeable acetylcholine nicotinic receptors | |||
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01314222) Diabetic Peripheral Neuropathic Pain (DPNP). U.S. National Institutes of Health. | |||
| REF 2 | EP patent application no. 2774991, Drug delivery system for use in the treatment or diagnosis of neurological disorders. | |||
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