Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00QXB
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| Former ID |
DIB009629
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| Drug Name |
WT1 peptide vaccine
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| Synonyms |
WT1 peptide vaccine (cancer); WT1 peptide vaccine (cancer), Charity Medical School of the Humboldt University of Berlin; Cancer vaccine (Wilms tumor gene 1 + KLH + GM-CSF advuvants), Humboldt University of Berlin
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| Drug Type |
Vaccine
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| Indication | leukaemia [ICD-11: 2A60-2B33; ICD-9: 208.9] | Phase 2 | [1] | |
| Company |
Charity Medical School of the Humboldt University of Berlin
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Wilms tumor protein (WT1) | Target Info | . | [2] |
| KEGG Pathway | Transcriptional misregulation in cancer | |||
| NetPath Pathway | FSH Signaling Pathway | |||
| IL5 Signaling Pathway | ||||
| Pathway Interaction Database | p73 transcription factor network | |||
| Regulation of Telomerase | ||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | |||
| Integrated Pancreatic Cancer Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01266083) Trial of a WT-1 Analog Peptide Vaccine in Patients With Acute Myeloid Leukemia (AML) or Acute Lymphoblastic Leukemia (ALL). U.S. National Institutes of Health. | |||
| REF 2 | Wilms' tumor protein 1 (WT1) peptide vaccination in AML patients: predominant TCR CDR3beta sequence associated with remission in one patient is detectable in other vaccinated patients. Cancer ImmunolImmunother. 2012 Mar;61(3):313-22. | |||
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