Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00SOZ
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| Former ID |
DIB001660
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| Drug Name |
Omidenepag isopropyl
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| Synonyms |
DE-117
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| Indication | Glaucoma/ocular hypertension [ICD-11: 9C61] | Approved | [1] | |
| Company |
Santen
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H28N6O4S
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| Canonical SMILES |
CC(C)OC(=O)CNC1=CC=CC(=N1)CN(CC2=CC=C(C=C2)N3C=CC=N3)S(=O)(=O)C4=CN=CC=C4
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| InChI |
1S/C26H28N6O4S/c1-20(2)36-26(33)17-28-25-8-3-6-22(30-25)19-31(37(34,35)24-7-4-13-27-16-24)18-21-9-11-23(12-10-21)32-15-5-14-29-32/h3-16,20H,17-19H2,1-2H3,(H,28,30)
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| InChIKey |
VIQCWEGEHRBLAC-UHFFFAOYSA-N
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| CAS Number |
CAS 1187451-19-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin E2 receptor EP2 (PTGER2) | Target Info | Agonist | [2] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Renin secretion | ||||
| Pathways in cancer | ||||
| Reactome | Prostanoid ligand receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Ovarian Infertility Genes | ||||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2022. Application Number: 215092. | |||
| REF 2 | Clinical pipeline report, company report or official report of Santen Pharmaceutical. | |||
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