Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00TBJ
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| Former ID |
DIB014810
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| Drug Name |
PF-271836
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| Synonyms |
PF-2721374; PF-383965; PF-534422; PF-603059; UK-210587; UK-252820; UK-451402; Oxytocin antagonists (premature labor, prostatic hyperplasia, sexual dysfunction); Oxytocin antagonists (premature labor, prostatic hyperplasia, sexual dysfunction), Pfizer
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| Indication | Female sexual arousal dysfunction [ICD-11: HA01.1; ICD-9: 302.7] | Investigative | [1] | |
| Company |
Pfizer Inc
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Oxytocin receptor (OTR) | Target Info | Antagonist | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Oxytocin signaling pathway | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Panther Pathway | Oxytocin receptor mediated signaling pathway | |||
| Reactome | Vasopressin-like receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Oxytocin signaling | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 369). | |||
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