Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00WYS
|
|||
| Former ID |
DNC010785
|
|||
| Drug Name |
3-(4-phenyl-6-(thiophen-2-yl)pyridin-2-yl)-phenol
|
|||
| Synonyms |
CHEMBL1094819
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H15NOS
|
|||
| Canonical SMILES |
C1=CC=C(C=C1)C2=CC(=NC(=C2)C3=CC=CS3)C4=CC(=CC=C4)O
|
|||
| InChI |
1S/C21H15NOS/c23-18-9-4-8-16(12-18)19-13-17(15-6-2-1-3-7-15)14-20(22-19)21-10-5-11-24-21/h1-14,23H
|
|||
| InChIKey |
ARUHBJGNLAPWGO-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA topoisomerase I (TOP1) | Target Info | Inhibitor | [1] |
| DNA topoisomerase II (TOP2) | Target Info | Inhibitor | [1] | |
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | DNA replication | |||
| Pathway Interaction Database | Caspase Cascade in Apoptosis | |||
| WikiPathways | Integrated Pancreatic Cancer Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl ... Bioorg Med Chem. 2010 May 1;18(9):3066-77. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.