Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00ZME
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| Former ID |
DNC008628
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| Drug Name |
1-((9H-Fluoren-2-yl)ethyl)-1H-imidazole
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| Synonyms |
CHEMBL501198; 1-((9H-Fluoren-2-yl)ethyl)-1H-imidazole; SCHEMBL8609682; QOKBMECMKDLYIV-UHFFFAOYSA-N; BDBM50272209; 1-[1-(9H-Fluoren-2-yl)ethyl]-1H-imidazole; 1-[1-(9H-fluoren-2-yl) ethyl]-1H-imidazole
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H16N2
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| Canonical SMILES |
CC(C1=CC2=C(C=C1)C3=CC=CC=C3C2)N4C=CN=C4
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| InChI |
1S/C18H16N2/c1-13(20-9-8-19-12-20)14-6-7-18-16(10-14)11-15-4-2-3-5-17(15)18/h2-10,12-13H,11H2,1H3
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| InChIKey |
QOKBMECMKDLYIV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 17-alpha-monooxygenase (S17AH) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Androgen biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| Prolactin signaling pathway | ||||
| Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
| Steroidogenesis | ||||
| Reactome | Androgen biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Steroid Biosynthesis | ||||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| Prostate Cancer | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxyl... Bioorg Med Chem. 2008 Aug 15;16(16):7715-27. | |||
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