Drug Information
Drug General Information | Top | |||
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Drug ID |
D01DOV
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Former ID |
DNC013388
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Drug Name |
(S)-2-Amino-N-cyclopentyl-7-mercaptoheptanamide
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Synonyms |
thiolate analogue, 26a; CHEMBL235911; SCHEMBL16338810; BDBM19139
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H24N2OS
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Canonical SMILES |
C1CCC(C1)NC(=O)C(CCCCCS)N
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InChI |
1S/C12H24N2OS/c13-11(8-2-1-5-9-16)12(15)14-10-6-3-4-7-10/h10-11,16H,1-9,13H2,(H,14,15)/t11-/m0/s1
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InChIKey |
BNEXTTBMNDFSSZ-NSHDSACASA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Histone deacetylase 6 (HDAC6) | Target Info | Inhibitor | [1] |
KEGG Pathway | Alcoholism | |||
Viral carcinogenesis | ||||
Pathway Interaction Database | Signaling events mediated by HDAC Class II | |||
Signaling events mediated by HDAC Class I | ||||
Reactome | NOTCH1 Intracellular Domain Regulates Transcription | |||
Constitutive Signaling by NOTCH1 PEST Domain Mutants | ||||
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | ||||
Assembly of the primary cilium | ||||
WikiPathways | Ectoderm Differentiation | |||
Neural Crest Differentiation | ||||
Cell Cycle |
References | Top | |||
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REF 1 | Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhib... J Med Chem. 2007 Nov 1;50(22):5425-38. |
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