Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01FCK
|
|||
| Former ID |
DIB008002
|
|||
| Drug Name |
Teglicar
|
|||
| Synonyms |
Reversible palmitoyltransferase inhibitor; ST-1326
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Diabetic complication [ICD-11: 5A2Y; ICD-9: 253.5, 588.1] | Discontinued in Phase 2 | [1] | |
| Company |
Sigma-Tau SpA
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C22H45N3O3
|
|||
| Canonical SMILES |
CCCCCCCCCCCCCCNC(=O)NC(CC(=O)[O-])C[N+](C)(C)C
|
|||
| InChI |
1S/C22H45N3O3/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-23-22(28)24-20(18-21(26)27)19-25(2,3)4/h20H,5-19H2,1-4H3,(H2-,23,24,26,27,28)/t20-/m1/s1
|
|||
| InChIKey |
BMZYTDRMCBZVNH-HXUWFJFHSA-N
|
|||
| CAS Number |
CAS 250694-07-6
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carnitine acyltransferase (CRAT) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017026) | |||
| REF 2 | Selective Reversible Inhibition of Liver Carnitine Palmitoyl-Transferase 1 by Teglicar Reduces Gluconeogenesis and Improves Glucose Homeostasis. Diabetes. 2011 February; 60(2): 644-651. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.