Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D01XFT
|
|||
Former ID |
DNC012135
|
|||
Drug Name |
3-(6-Amino-purin-9-yl)-8-phenyl-octan-2-ol
|
|||
Synonyms |
CHEMBL43742; 3-(6-Amino-purin-9-yl)-8-phenyl-octan-2-ol; SCHEMBL7458088; ZINC13835547; BDBM50070645; (2S,3R)-3-(6-Amino-purin-9-yl)-8-phenyl-octan-2-ol
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C19H25N5O
|
|||
Canonical SMILES |
CC(C(CCCCCC1=CC=CC=C1)N2C=NC3=C(N=CN=C32)N)O
|
|||
InChI |
1S/C19H25N5O/c1-14(25)16(11-7-3-6-10-15-8-4-2-5-9-15)24-13-23-17-18(20)21-12-22-19(17)24/h2,4-5,8-9,12-14,16,25H,3,6-7,10-11H2,1H3,(H2,20,21,22)/t14-,16+/m0/s1
|
|||
InChIKey |
JVHQYTUGDFGNES-GOEBONIOSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Adenosine deaminase (ADA) | Target Info | Inhibitor | [1] |
BioCyc | Purine nucleotides degradation | |||
Purine deoxyribonucleosides degradation | ||||
Purine ribonucleosides degradation to ribose-1-phosphate | ||||
Adenosine nucleotides degradation | ||||
Superpathway of purine nucleotide salvage | ||||
Adenine and adenosine salvage III | ||||
KEGG Pathway | Purine metabolism | |||
Metabolic pathways | ||||
Primary immunodeficiency | ||||
NetPath Pathway | TCR Signaling Pathway | |||
IL2 Signaling Pathway | ||||
Panther Pathway | Adenine and hypoxanthine salvage pathway | |||
Pathwhiz Pathway | Purine Metabolism | |||
Pathway Interaction Database | p73 transcription factor network | |||
C-MYB transcription factor network | ||||
Validated transcriptional targets of deltaNp63 isoforms | ||||
Validated transcriptional targets of TAp63 isoforms | ||||
Reactome | Purine salvage | |||
WikiPathways | Metabolism of nucleotides |
References | Top | |||
---|---|---|---|---|
REF 1 | Adenosine deaminase inhibitors: synthesis and biological evaluation of unsaturated, aromatic, and oxo derivatives of (+)-erythro-9-(2'S-hydroxy-3'R... J Med Chem. 2000 Nov 30;43(24):4694-700. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.