Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02ADJ
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| Former ID |
DIB009162
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| Drug Name |
Apolipoprotein E
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| Synonyms |
Apolipoprotein E, Bio-Technology General; Apo-A4, Bio-Technology General; Apo-E, Bio-Technology General; Apolipoprotein-A4, Bio-Technology General
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| Indication | Glaucoma/ocular hypertension [ICD-11: 9C61; ICD-9: 365] | Terminated | [1] | |
| Company |
Savient Pharmaceuticals Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Apolipoprotein E (APOE) | Target Info | Modulator | [2] |
| KEGG Pathway | Alzheimer's disease | |||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Wnt Signaling Pathway | ||||
| Reactome | Chylomicron-mediated lipid transport | |||
| HDL-mediated lipid transport | ||||
| Scavenging by Class A Receptors | ||||
| Retinoid metabolism and transport | ||||
| WikiPathways | Statin Pathway | |||
| Apoptosis-related network due to altered Notch3 in ovarian cancer | ||||
| Binding and Uptake of Ligands by Scavenger Receptors | ||||
| Visual phototransduction | ||||
| Lipid digestion, mobilization, and transport | ||||
| Alzheimers Disease | ||||
| Vitamin B12 Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000261) | |||
| REF 2 | Apolipoprotein E: a potent inhibitor of endothelial and tumor cell proliferation. J Cell Biochem. 1994 Mar;54(3):299-308. | |||
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