Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02AFI
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| Former ID |
DNC014358
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| Drug Name |
1-D-glucopyranosyl cytosine
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| Synonyms |
1-D-glucopyranosyl cytosine; CHEMBL1096136; 4-Amino-1-Beta-D-Glucopyranosylpyrimidin-2(1h)-One; 1-D-glucopyranosyl-cytosine; SCHEMBL7520145; 1-beta-D-Glucopyranosylcytosine; BDBM50316588
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H15N3O6
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| Canonical SMILES |
C1=CN(C(=O)N=C1N)C2C(C(C(C(O2)CO)O)O)O
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| InChI |
1S/C10H15N3O6/c11-5-1-2-13(10(18)12-5)9-8(17)7(16)6(15)4(3-14)19-9/h1-2,4,6-9,14-17H,3H2,(H2,11,12,18)/t4-,6-,7+,8-,9-/m1/s1
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| InChIKey |
YYUQXKHCNLFJNF-DDIGBBAMSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glycogen phosphorylase muscle form (GP) | Target Info | Inhibitor | [1] |
| BioCyc | Glycogenolysis | |||
| KEGG Pathway | Starch and sucrose metabolism | |||
| Metabolic pathways | ||||
| Insulin signaling pathway | ||||
| Glucagon signaling pathway | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| WikiPathways | Glycogen Metabolism | |||
| Metabolism of carbohydrates | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modellin... Bioorg Med Chem. 2010 May 15;18(10):3413-25. | |||
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