Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02BXG
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| Former ID |
DNC012290
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| Drug Name |
1-Benzo[b]thiophen-2-yl-cyclohexylamine
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| Synonyms |
Cyclohexanamine, 1-benzo[b]thien-2-yl-; CHEMBL18556; 143603-26-3; NSC708121; ACMC-20bbzv; 1-Benzo[b]thiophen-2-yl-cyclohexylamine; AC1L9GJR; SCHEMBL7095248; CTK0B4318; DTXSID80327969; HYVMNAZTYJDWIZ-UHFFFAOYSA-N; ZINC1657638; BDBM50040190; AKOS030613260; NSC-708121; 1-(1-Benzothien-2-yl)cyclohexanamine #; Thionaphthene, 2-[1-aminocyclohex-1-yl]-; 1-(1-benzothiophen-2-yl)cyclohexan-1-amine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H17NS
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| Canonical SMILES |
C1CCC(CC1)(C2=CC3=CC=CC=C3S2)N
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| InChI |
1S/C14H17NS/c15-14(8-4-1-5-9-14)13-10-11-6-2-3-7-12(11)16-13/h2-3,6-7,10H,1,4-5,8-9,15H2
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| InChIKey |
HYVMNAZTYJDWIZ-UHFFFAOYSA-N
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| CAS Number |
CAS 143603-26-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dopamine transporter (DAT) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Dopaminergic synapse | |||
| Parkinson's disease | ||||
| Cocaine addiction | ||||
| Amphetamine addiction | ||||
| Alcoholism | ||||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| Parkinson disease | ||||
| Dopamine receptor mediated signaling pathway | ||||
| Pathway Interaction Database | Alpha-synuclein signaling | |||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | Monoamine Transport | |||
| NRF2 pathway | ||||
| Dopaminergic Neurogenesis | ||||
| Parkinsons Disease Pathway | ||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||||
| Neurotransmitter Clearance In The Synaptic Cleft | ||||
| References | Top | |||
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| REF 1 | Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-bin... J Med Chem. 1993 Apr 30;36(9):1188-93. | |||
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