Target and Pathway |
Top |
Target(s) |
PI3-kinase gamma (PIK3CG) |
Target Info
|
Inhibitor |
[1] |
Serine/threonine-protein kinase mTOR (mTOR) |
Target Info
|
Inhibitor |
[2] |
KEGG Pathway
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Inositol phosphate metabolism
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ErbB signaling pathway
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Ras signaling pathway
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Rap1 signaling pathway
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cGMP-PKG signaling pathway
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cAMP signaling pathway
|
Chemokine signaling pathway
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HIF-1 signaling pathway
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FoxO signaling pathway
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Phosphatidylinositol signaling system
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Sphingolipid signaling pathway
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mTOR signaling pathway
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PI3K-Akt signaling pathway
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AMPK signaling pathway
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Apoptosis
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Adrenergic signaling in cardiomyocytes
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VEGF signaling pathway
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Osteoclast differentiation
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Focal adhesion
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Signaling pathways regulating pluripotency of stem cells
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Platelet activation
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Toll-like receptor signaling pathway
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Jak-STAT signaling pathway
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Natural killer cell mediated cytotoxicity
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T cell receptor signaling pathway
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B cell receptor signaling pathway
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Fc epsilon RI signaling pathway
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Fc gamma R-mediated phagocytosis
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TNF signaling pathway
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Leukocyte transendothelial migration
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Neurotrophin signaling pathway
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Cholinergic synapse
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Inflammatory mediator regulation of TRP channels
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Regulation of actin cytoskeleton
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Insulin signaling pathway
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Progesterone-mediated oocyte maturation
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Estrogen signaling pathway
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Prolactin signaling pathway
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Thyroid hormone signaling pathway
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Oxytocin signaling pathway
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Regulation of lipolysis in adipocytes
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Type II diabetes mellitus
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Non-alcoholic fatty liver disease (NAFLD)
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Aldosterone-regulated sodium reabsorption
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Carbohydrate digestion and absorption
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Bacterial invasion of epithelial cells
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Chagas disease (American trypanosomiasis)
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Toxoplasmosis
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Amoebiasis
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Hepatitis C
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Hepatitis B
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Measles
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Influenza A
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HTLV-I infection
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Epstein-Barr virus infection
|
Pathways in cancer
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Viral carcinogenesis
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Proteoglycans in cancer
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MicroRNAs in cancer
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Colorectal cancer
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Renal cell carcinoma
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Pancreatic cancer
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Endometrial cancer
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Glioma
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Prostate cancer
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Melanoma
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Chronic myeloid leukemia
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Acute myeloid leukemia
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Small cell lung cancer
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Non-small cell lung cancer
|
Central carbon metabolism in cancer
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Choline metabolism in cancer
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Adipocytokine signaling pathway
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Panther Pathway
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Hypoxia response via HIF activation
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Interleukin signaling pathway
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Pathwhiz Pathway
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Inositol Metabolism
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Phosphatidylinositol Phosphate Metabolism
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Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
|
Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
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Fc Epsilon Receptor I Signaling in Mast Cells
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Leucine Stimulation on Insulin Signaling
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Pathway Interaction Database
|
IL4-mediated signaling events
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Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
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IL12-mediated signaling events
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CDC42 signaling events
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LKB1 signaling events
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Regulation of Telomerase
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mTOR signaling pathway
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CXCR4-mediated signaling events
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EGFR-dependent Endothelin signaling events
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IL2 signaling events mediated by PI3K
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IFN-gamma pathway
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ErbB1 downstream signaling
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ErbB2/ErbB3 signaling events
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CXCR3-mediated signaling events
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Class I PI3K signaling events mediated by Akt
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Reactome
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PI3K Cascade
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GPVI-mediated activation cascade
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Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
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PI3K events in ERBB4 signaling
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PIP3 activates AKT signaling
|
GAB1 signalosome
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PI3K events in ERBB2 signaling
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PI3K/AKT activation
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Role of phospholipids in phagocytosis
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Tie2 Signaling
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Constitutive Signaling by Aberrant PI3K in Cancer
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DAP12 signaling
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Role of LAT2/NTAL/LAB on calcium mobilization
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Nephrin interactions
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Costimulation by the CD28 family
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CD28 dependent PI3K/Akt signaling
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G beta:gamma signalling through PI3Kgamma
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G alpha (q) signalling events
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G alpha (12/13) signalling events
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VEGFA-VEGFR2 Pathway
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Interleukin-3, 5 and GM-CSF signaling
|
Constitutive Signaling by EGFRvIII
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PI-3K cascade:FGFR1
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PI-3K cascade:FGFR2
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PI-3K cascade:FGFR3
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PI-3K cascade:FGFR4
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Interleukin receptor SHC signaling
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Regulation of signaling by CBL
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Macroautophagy
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mTORC1-mediated signalling
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HSF1-dependent transactivation
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VEGFR2 mediated vascular permeability
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TP53 Regulates Metabolic Genes
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Constitutive Signaling by AKT1 E17K in Cancer
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WikiPathways
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Toll-like receptor signaling pathway
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Serotonin HTR1 Group and FOS Pathway
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DNA Damage Response (only ATM dependent)
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G13 Signaling Pathway
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Regulation of Actin Cytoskeleton
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Insulin Signaling
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IL-4 Signaling Pathway
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Copper homeostasis
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Signaling of Hepatocyte Growth Factor Receptor
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Transcriptional activation by NRF2
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IL1 and megakaryotyces in obesity
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Signaling by ERBB4
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Signaling by ERBB2
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Fc epsilon receptor (FCERI) signaling
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PI Metabolism
|
Interleukin-2 signaling
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Fcgamma receptor (FCGR) dependent phagocytosis
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Signaling by SCF-KIT
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DAP12 interactions
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Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
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Gastrin-CREB signalling pathway via PKC and MAPK
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PIP3 activates AKT signaling
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Integrated Pancreatic Cancer Pathway
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Prostate Cancer
|
Signaling Pathways in Glioblastoma
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TSLP Signaling Pathway
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Regulation of Microtubule Cytoskeleton
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TSH signaling pathway
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SREBP signalling
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TCR signaling
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Signaling by PDGF
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Signaling by Insulin receptor
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Signaling by FGFR
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Signaling by EGFR
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NGF signalling via TRKA from the plasma membrane
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Nephrin interactions
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Interleukin-3, 5 and GM-CSF signaling
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GPVI-mediated activation cascade
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GPCR downstream signaling
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Costimulation by the CD28 family
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Cell surface interactions at the vascular wall
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MicroRNAs in cardiomyocyte hypertrophy
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Angiogenesis
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Regulation of toll-like receptor signaling pathway
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AMPK Signaling
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ErbB Signaling Pathway
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Senescence and Autophagy in Cancer
|
Interferon type I signaling pathways
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EGF/EGFR Signaling Pathway
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Wnt Signaling Pathway Netpath
|
Extracellular vesicle-mediated signaling in recipient cells
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Cardiac Hypertrophic Response
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Polycystic Kidney Disease Pathway
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Alpha 6 Beta 4 signaling pathway
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BDNF signaling pathway
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Oncostatin M Signaling Pathway
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FSH signaling pathway
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Leptin signaling pathway
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RANKL/RANK Signaling Pathway
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SREBF and miR33 in cholesterol and lipid homeostasis
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Integrated Breast Cancer Pathway
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Type II diabetes mellitus
|
TOR Signaling
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