Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02EZM
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| Former ID |
DNAP001689
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| Drug Name |
Fospropofol disodium
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| Synonyms |
Lusedra (TN)
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| Drug Type |
Small molecular drug
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| Indication | Monitored anaesthesia care [ICD-11: N.A.] | Approved | [1], [2] | |
| Company |
Eisai
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| Structure |
 |
Download2D MOL |
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| Formula |
C13H19Na2O5P
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| Canonical SMILES |
CC(C)C1=C(C(=CC=C1)C(C)C)OCOP(=O)([O-])[O-].[Na+].[Na+]
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| InChI |
1S/C13H21O5P.2Na/c1-9(2)11-6-5-7-12(10(3)4)13(11)17-8-18-19(14,15)16;;/h5-7,9-10H,8H2,1-4H3,(H2,14,15,16);;/q;2*+1/p-2
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| InChIKey |
LWYLQNWMSGFCOZ-UHFFFAOYSA-L
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| CAS Number |
CAS 258516-87-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ADReCS Drug ID | BADD_D00972 | |||
| SuperDrug ATC ID |
N01AX10
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Modulator | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2008 FDA drug approvals. Nat Rev Drug Discov. 2009 Feb;8(2):93-6. | |||
| REF 2 | General anesthetic potencies of a series of propofol analogs correlate with potency for potentiation of gamma-aminobutyric acid (GABA) current at the GABA(A) receptor but not with lipid solubility. JPharmacol Exp Ther. 2001 Apr;297(1):338-51. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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