Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02VMJ
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| Former ID |
DNC010893
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| Drug Name |
TRICLABENDAZOLE
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| Synonyms |
Triclabendazole; 68786-66-3; Fasinex; 6-Chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzo[d]imidazole; C14H9Cl3N2OS; Triclabendazolum [INN-Latin]; Triclabendazol [INN-Spanish]; CCRIS 8988; UNII-4784C8E03O; CGA 89317; 5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole; CPD000466357; MLS001424101; CHEMBL1086440; 6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole; 4784C8E03O; NCGC00164610-01; Triclabendazole, 98%; SMR000466357; AK-68238; 5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)benzimidazole
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| Drug Type |
Small molecular drug
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| Indication | Helminth infection [ICD-11: 1F90.0; ICD-10: A00-B99; ICD-9: 001-139] | Approved | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H9Cl3N2OS
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| Canonical SMILES |
CSC1=NC2=CC(=C(C=C2N1)Cl)OC3=C(C(=CC=C3)Cl)Cl
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| InChI |
1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
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| InChIKey |
NQPDXQQQCQDHHW-UHFFFAOYSA-N
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| CAS Number |
CAS 68786-66-3
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:94759
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| SuperDrug ATC ID |
P02BX04
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Trypanosoma Cruzipain (Trypano CYSP) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Colloid formation by drugs in simulated intestinal fluid. J Med Chem. 2010 May 27;53(10):4259-65. | |||
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