Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02ZCP
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| Former ID |
DNC002967
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| Drug Name |
5-Phenylsulfanyl-2,4-Quinazolinediamine
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| Synonyms |
5-Phenylsulfanyl-2,4-quinazolinediamine; 5-PHENYLSULFANYL-2,4-QUINAZOLINEDIAMINE; TCMDC-131943; 5-(phenylsulfanyl)quinazoline-2,4-diamine; 5-phenylsulfanylquinazoline-2,4-diamine; TQ3; AC1L9JD6; SCHEMBL2125192; CHEMBL100239; BDBM18045; GW997; ZINC5974663; 5-Phenylthioquinazoline-2,4-diamine; 2,4-Diamino-5-phenylthio-quinazoline; DB04163; 5-Phenylsulfanyl-quinazoline-2,4-diamine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H12N4S
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| Canonical SMILES |
C1=CC=C(C=C1)SC2=CC=CC3=C2C(=NC(=N3)N)N
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| InChI |
1S/C14H12N4S/c15-13-12-10(17-14(16)18-13)7-4-8-11(12)19-9-5-2-1-3-6-9/h1-8H,(H4,15,16,17,18)
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| InChIKey |
BUFDQCGCADQQQY-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Polypeptide deformylase (PDF) | Target Info | Inhibitor | [1], [2] |
| Pathwhiz Pathway | Folate Metabolism | |||
| Pterine Biosynthesis | ||||
| Reactome | E2F mediated regulation of DNA replication | |||
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | ||||
| Metabolism of folate and pterines | ||||
| G1/S-Specific Transcription | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
| REF 2 | X-Ray crystal structures of Candida albicans dihydrofolate reductase: high resolution ternary complexes in which the dihydronicotinamide moiety of ... J Med Chem. 2001 Aug 30;44(18):2928-32. | |||
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