Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03BZN
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| Former ID |
DIB002059
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| Drug Name |
Sodium taurocholate
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| Synonyms |
Sodium taurocholate (rectal gel, diabetes/ obesity)
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| Drug Type |
Small molecular drug
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| Indication | Type-2 diabetes [ICD-11: 5A11; ICD-9: 250] | Phase 1/2 | [1] | |
| Company |
Satiogen Pharmaceuticals Inc
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| Structure |
 |
Download2D MOL
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| Formula |
C26H44NNaO7S
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| Canonical SMILES |
CC(CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C.[Na+]
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| InChI |
1S/C26H45NO7S.Na/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;/m1./s1
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| InChIKey |
JAJWGJBVLPIOOH-IZYKLYLVSA-M
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| CAS Number |
CAS 145-42-6
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:36276
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | G-protein coupled bile acid receptor 1 (GPBAR1) | Target Info | Modulator | [1] |
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (s) signalling events | ||||
| WikiPathways | GPCR ligand binding | |||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism.Acta Pharmaceutica Sinica B Volume 5, Issue 2, March 2015, Pages 151-157. | |||
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