Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03DRM
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| Former ID |
DIB020721
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| Drug Name |
AS-604850
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| Synonyms |
AS 604850; PI 3-Kgamma inhibitor II
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C11H5F2NO4S
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| Canonical SMILES |
C1=CC2=C(C=C1C=C3C(=O)NC(=O)S3)OC(O2)(F)F
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| InChI |
1S/C11H5F2NO4S/c12-11(13)17-6-2-1-5(3-7(6)18-11)4-8-9(15)14-10(16)19-8/h1-4H,(H,14,15,16)/b8-4-
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| InChIKey |
SRLVNYDXMUGOFI-YWEYNIOJSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7886391, 8026260, 11041350, 15344777, 24724381, 26759373, 39320394, 46393780, 50344552, 53787404, 90341251, 99302751, 99443974, 104247716, 113870638, 121361235, 135727846, 136367482, 136368091, 141309641, 144115627, 160968577, 162011951, 163564459, 163687480, 164023423, 175607430, 177749080, 178102646, 204380105, 223704483, 227980012, 252457873
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| ChEBI ID |
CHEBI:94690
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6024). | |||
| REF 2 | Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat Med. 2005 Sep;11(9):936-43. | |||
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