Drug Information
Drug General Information | Top | |||
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Drug ID |
D03HLK
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Former ID |
DIB001177
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Drug Name |
PRT-060096
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Synonyms |
PRT-060280; PRT-060288; PRT-060289; PRT-060392; PRT-060592; PRT-060674; PRT-061105; PRT-061106; PRT-061110; PRT-061171; Non-sulfonylurea P2Y12 antagonists (cardiovascular disease); Non-sulfonylurea P2Y12 antagonists (cardiovascular disease), Portola
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Indication | Cardiovascular disease [ICD-11: BA00-BE2Z; ICD-10: I00-I99] | Investigative | [1] | |
Company |
Portola Pharmaceuticals Inc
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | P2Y purinoceptor 12 (P2RY12) | Target Info | Antagonist | [1] |
KEGG Pathway | Platelet activation | |||
Reactome | P2Y receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Signal amplification | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 328). |
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