Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03IWW
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| Former ID |
DNC012869
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| Drug Name |
(S)-Piperidine-3-carboxylic acid
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| Synonyms |
59045-82-8; (S)-(+)-Nipecotic acid; (3S)-piperidine-3-carboxylic acid; (S)-nipecotic acid; (3S)-nipecotic acid; (S)-(+)-3-Piperidinecarboxylic acid; (S)-hexahydronicotinic acid; L(+)-NIPECOTIC ACID; (3S)-hexahydronicotinic acid; CHEBI:222169; (3S)-3-piperidinecarboxylic acid; 3-Piperidinecarboxylic acid, (3S)-; (S)-(+)-PIPERIDINE-3-CARBOXYLIC ACID; UNII-2635N2PS4Q; (3S)-(+)-piperidine-3-carboxylic acid; L-PIPERIDINE-3-CARBOXYLIC ACID
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C6H11NO2
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| Canonical SMILES |
C1CC(CNC1)C(=O)O
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| InChI |
1S/C6H11NO2/c8-6(9)5-2-1-3-7-4-5/h5,7H,1-4H2,(H,8,9)/t5-/m0/s1
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| InChIKey |
XJLSEXAGTJCILF-YFKPBYRVSA-N
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| CAS Number |
CAS 59045-82-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:222169
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA transporter GAT-1 (SLC6A1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | GABAergic synapse | |||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | Monoamine Transport | |||
| NRF2 pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel secoergoline derivatives inhibit both GABA and glutamate uptake in rat brain homogenates: synthesis, in vitro pharmacology, and modeling. J Med Chem. 2004 Nov 4;47(23):5620-9. | |||
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