Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03PLV
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| Former ID |
DNC003221
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| Drug Name |
1-Deaza-Adenosine
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| Synonyms |
1-Deazaadenosine; 1-deaza-adenosine; 14432-09-8; CHEMBL115824; 1DA; 1add; 1-Deaza-A; AC1L4ME8; AC1Q4XY1; adenosine-N,1,3-15N3; SCHEMBL18490353; A-d-ribofuranosyl)-3h-imidazo[4,5-b]pyridin-7-amine; MolPort-023-278-902; 3H-Imidazo(4,5-b)pyridin-7-amine, 3-beta-D-ribofuranosyl-; ZINC3814313; PDSP1_001078; BDBM50060165; PDSP2_001062; AKOS024458188; DB04218; NCGC00163308-01; 3- -D-Ribofuranosyl-3H-imidazo[4,5-b]pyridin-7-amine; 3-beta-D-ribofuranosyl-3H-imidazo[4,5-b]pyridin-7-amine; 3H-Imidazo[4,5-B]Pyridine, 7-Amino-3-ss-D-Ribof
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H14N4O4
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| Canonical SMILES |
C1=CN=C2C(=C1N)N=CN2C3C(C(C(O3)CO)O)O
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| InChI |
1S/C11H14N4O4/c12-5-1-2-13-10-7(5)14-4-15(10)11-9(18)8(17)6(3-16)19-11/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13)/t6-,8-,9-,11-/m1/s1
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| InChIKey |
NVUDDRWKCUAERS-PNHWDRBUSA-N
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| CAS Number |
CAS 14432-09-8
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine deaminase (ADA) | Target Info | Inhibitor | [1] |
| BioCyc | Purine nucleotides degradation | |||
| Purine deoxyribonucleosides degradation | ||||
| Purine ribonucleosides degradation to ribose-1-phosphate | ||||
| Adenosine nucleotides degradation | ||||
| Superpathway of purine nucleotide salvage | ||||
| Adenine and adenosine salvage III | ||||
| KEGG Pathway | Purine metabolism | |||
| Metabolic pathways | ||||
| Primary immunodeficiency | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Panther Pathway | Adenine and hypoxanthine salvage pathway | |||
| Pathwhiz Pathway | Purine Metabolism | |||
| Pathway Interaction Database | p73 transcription factor network | |||
| C-MYB transcription factor network | ||||
| Validated transcriptional targets of deltaNp63 isoforms | ||||
| Validated transcriptional targets of TAp63 isoforms | ||||
| Reactome | Purine salvage | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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