Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03QGL
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| Former ID |
DNC004374
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| Drug Name |
DALTROBAN
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| Synonyms |
79094-20-5; BM-13505; Daltrobanum; SKF 96148; BM 13505; UNII-S25VDY08ZC; BM 13.505; C16H16ClNO4S; SKF-96148; F 96148; S25VDY08ZC; CHEMBL71685; 4-(2-(4-Chlorophenylsulfonylamino)ethyl)phenylacetic acid; 4-(2-(4-Chlorobenzenesulfonylamino)ethyl)benzeneacetic acid; F-96148; NCGC00165787-02; 2-(4-(2-(4-chlorophenylsulfonamido)ethyl)phenyl)acetic acid; 2-[4-[2-[(4-chlorophenyl)sulfonylamino]ethyl]phenyl]acetic acid; DSSTox_RID_81670; DSSTox_CID_26501; DSSTox_GSID_46501; 105218-03-9; Benzeneacetic acid, 4-(2-((
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C16H16ClNO4S
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| Canonical SMILES |
C1=CC(=CC=C1CCNS(=O)(=O)C2=CC=C(C=C2)Cl)CC(=O)O
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| InChI |
1S/C16H16ClNO4S/c17-14-5-7-15(8-6-14)23(21,22)18-10-9-12-1-3-13(4-2-12)11-16(19)20/h1-8,18H,9-11H2,(H,19,20)
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| InChIKey |
IULOBWFWYDMECP-UHFFFAOYSA-N
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| CAS Number |
CAS 79094-20-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7980463, 8183594, 12013863, 14827916, 24724468, 29217545, 34718349, 47205878, 47731232, 47880083, 50064106, 50111705, 50291765, 57313603, 85208974, 103266899, 103916977, 104304662, 117609918, 125824441, 126651901, 126684326, 128222123, 134222427, 134341579, 135014547, 135065498, 135650157, 137035306, 144205815, 162178983, 162247901, 164175138, 164788317, 170466199, 172876507, 179151178, 184545795, 198977445, 223681779, 223860385, 226648554, 241138652, 242467035, 252347810, 252451135
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Thromboxane A2 receptor (TBXA2R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Platelet activation | ||||
| Reactome | Prostanoid ligand receptors | |||
| G alpha (q) signalling events | ||||
| G alpha (12/13) signalling events | ||||
| Thromboxane signalling through TP receptor | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Small Ligand GPCRs | ||||
| Signal amplification | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
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| REF 1 | Synthesis and thromboxane A2/prostaglandin H2 receptor antagonistic activity of phenol derivatives. J Med Chem. 1992 Jun 12;35(12):2202-9. | |||
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