Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03SFB
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| Former ID |
DNC010226
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| Drug Name |
2-Methyl-1(3)H-anthrasimidazole-6,11-dione
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| Synonyms |
AC1MZY8L; CHEMBL594892; SCHEMBL17702673; MolPort-002-517-242; MolPort-000-752-121; ZINC9353066; AKOS030496241; MCULE-7367469235; 2-methyl-3H-naphtho[3,2-e]benzimidazole-6,11-dione
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H10N2O2
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| Canonical SMILES |
CC1=NC2=C(N1)C=CC3=C2C(=O)C4=CC=CC=C4C3=O
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| InChI |
1S/C16H10N2O2/c1-8-17-12-7-6-11-13(14(12)18-8)16(20)10-5-3-2-4-9(10)15(11)19/h2-7H,1H3,(H,17,18)
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| InChIKey |
IXPPRTBZHPTQCM-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | Inhibitor | [1] |
| KEGG Pathway | HTLV-I infection | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
| Regulation of Telomerase | ||||
| IL2 signaling events mediated by PI3K | ||||
| Regulation of nuclear beta catenin signaling and target gene transcription | ||||
| HIF-1-alpha transcription factor network | ||||
| Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
| WikiPathways | TGF beta Signaling Pathway | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| Telomere Maintenance | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,1... Bioorg Med Chem. 2009 Nov 1;17(21):7418-28. | |||
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