Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03TYE
|
|||
| Former ID |
DNC012348
|
|||
| Drug Name |
PT-108
|
|||
| Synonyms |
149487-94-5; Thiourea, N-(2-(2,6-difluorophenyl)ethyl)-N'-(5-methyl-2-pyridinyl)-; 1-[2-(2,6-difluorophenyl)ethyl]-3-(5-methylpyridin-2-yl)thiourea; PETT Analog 58; Thiourea, N-[2-(2,6-difluorophenyl)ethyl]-N'-(5-methyl-2-pyridinyl)-; PT-108; AC1MHDL5; BDBM1891; CHEMBL398766; DTXSID40164312; ZINC13744917; N-(2-(2,6-Difluorophenyl)ethyl)-N -(2-(5-methylpyridyl))thiourea
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C15H15F2N3S
|
|||
| Canonical SMILES |
CC1=CN=C(C=C1)NC(=S)NCCC2=C(C=CC=C2F)F
|
|||
| InChI |
1S/C15H15F2N3S/c1-10-5-6-14(19-9-10)20-15(21)18-8-7-11-12(16)3-2-4-13(11)17/h2-6,9H,7-8H2,1H3,(H2,18,19,20,21)
|
|||
| InChIKey |
FIASQQMTLFRFPZ-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 149487-94-5
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Phenethylthiazolethiourea (PETT) compounds, a new class of HIV-1 reverse transcriptase inhibitors. 1. Synthesis and basic structure-activity relati... J Med Chem. 1995 Dec 8;38(25):4929-36. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.