Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03XYW
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| Former ID |
DAP000619
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| Drug Name |
Fenoprofen
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| Synonyms |
Fenoprofene; Fenoprofeno; Fenoprofenum; Feprona; Nalfon; Nalgesic; Feneprofen calcium salt dihydrate; Fenoprofen calcium; Fenoprofen calcium hydrate; Lilly 53838; Fenoprofen Dihydrate, Calcium Salt; Fenoprofene [INN-French]; Fenoprofeno [INN-Spanish]; Fenoprofenum [INN-Latin]; Fenopron (TN); Fenoprofen (USAN/INN); Fenoprofen [USAN:BAN:INN]; Alpha-(m-phenoxyphenyl)propionic acid; Alpha-Methyl-3-phenoxybenzeneacetic acid; (+-)-2-(3-Phenoxyphenyl)propionic acid; (+-)-m-Phenoxyhydratropic acid; 2-(3-Phenoxyphenyl)propanoic acid; 2-(3-Phenoxyphenyl)propionic acid; 2-(m-phenoxyphenyl)propionic acid; 2-[3-(phenyloxy)phenyl]propanoic acid
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| Drug Type |
Small molecular drug
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| Indication | Rheumatoid arthritis [ICD-11: FA20] | Approved | [1], [2] | |
| Therapeutic Class |
Antiinflammatory Agents
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| Company |
Typharm Limited
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| Structure |
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Download2D MOL |
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| Formula |
C15H14O3
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| Canonical SMILES |
CC(C1=CC(=CC=C1)OC2=CC=CC=C2)C(=O)O
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| InChI |
1S/C15H14O3/c1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13/h2-11H,1H3,(H,16,17)
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| InChIKey |
RDJGLLICXDHJDY-UHFFFAOYSA-N
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| CAS Number |
CAS 29679-58-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9210, 5309236, 7849409, 7979222, 8149698, 8152124, 10518387, 11336023, 11361262, 11364146, 11366708, 11369270, 11371959, 11374615, 11377432, 11462234, 11466782, 11467902, 11485138, 11486443, 11489207, 11490725, 11492823, 11495066, 14970762, 26612152, 26679731, 26748467, 26748468, 29222477, 46504597, 47216824, 47291184, 47515366, 47662338, 48110501, 48185044, 48416004, 49698760, 49977398, 50295410, 53787232, 57321739, 92124283, 92307537, 92309134, 99301936, 103158206, 103401163, 103825404
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| ChEBI ID |
CHEBI:5004
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| ADReCS Drug ID | BADD_D00877 ; BADD_D00878 | |||
| SuperDrug ATC ID |
M01AE04
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| SuperDrug CAS ID |
cas=031879057
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin G/H synthase (COX) | Target Info | Inhibitor | [3], [4] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4820). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 072267. | |||
| REF 3 | The aryl propionic acid R-flurbiprofen selectively induces p75NTR-dependent decreased survival of prostate tumor cells. Cancer Res. 2007 Apr 1;67(7):3254-62. | |||
| REF 4 | Immunomodulatory effect of nonsteroidal anti-inflammatory drugs (NSAIDs) at the clinically available doses. Arch Pharm Res. 2007 Jan;30(1):64-74. | |||
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