Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04JNR
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| Former ID |
DNC001329
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| Drug Name |
SIB-1765F
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| Synonyms |
SIB 1765F; Pyridine, 3-ethynyl-5-(1-methyl-2-pyrrolidinyl)-, (E)-2-butenedioate (1:1); Pyridine, 3-ethynyl-5-(1-methyl-2-pyrrolidinyl)-, (2E)-2-butenedioate (1:1); C12H14N2.C4H4O4; AC1O5WWQ; SCHEMBL194945; SCHEMBL3099334; SIB 1508Y, fumarate, E-isomer; 179120-52-6; LS-173698
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C16H18N2O4
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| Canonical SMILES |
CN1CCCC1C2=CN=CC(=C2)C#C.C(=CC(=O)O)C(=O)O
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| InChI |
1S/C12H14N2.C4H4O4/c1-3-10-7-11(9-13-8-10)12-5-4-6-14(12)2;5-3(6)1-2-4(7)8/h1,7-9,12H,4-6H2,2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
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| InChIKey |
BCPPKHPWLRPWBJ-WLHGVMLRSA-N
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| CAS Number |
CAS 179120-52-6
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nicotinic acetylcholine receptor (nAChR) | Target Info | Agonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Highly sodium permeable acetylcholine nicotinic receptors | |||
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| References | Top | |||
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| REF 1 | Interactions between a novel cholinergic ion channel agonist, SIB-1765F and L-DOPA in the reserpine model of Parkinson's disease in rats. J Pharmacol Exp Ther. 1997 Jan;280(1):393-401. | |||
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