Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04KMQ
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| Former ID |
DIB001185
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| Drug Name |
GSK3117391
|
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| Drug Type |
Small molecular drug
|
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| Indication | Rheumatoid arthritis [ICD-11: FA20] | Phase 1 | [1] | |
| Company |
Glaxosmithkline
|
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H33N3O4
|
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| Canonical SMILES |
C1CCC(CC1)C(C(=O)OC2CCCC2)NCC3=CN=C(C=C3)CCC(=O)NO
|
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| InChI |
1S/C22H33N3O4/c26-20(25-28)13-12-18-11-10-16(14-23-18)15-24-21(17-6-2-1-3-7-17)22(27)29-19-8-4-5-9-19/h10-11,14,17,19,21,24,28H,1-9,12-13,15H2,(H,25,26)/t21-/m0/s1
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| InChIKey |
AFDPFLDWOXXHQM-NRFANRHFSA-N
|
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| CAS Number |
CAS 1018673-42-1
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histone deacetylase (HDAC) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of GlaxoSmithKline. | |||
| REF 2 | The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet. 2009 January; 10(1): 32-42. | |||
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