Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04MKQ
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| Former ID |
DNC012104
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| Drug Name |
(Amino-phenyl-methyl)-phosphinic acid
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| Synonyms |
Phosphinic acid, (aminophenylmethyl)-; 126529-62-2; 1-amino-1-phenylmethylphosphinic acid; ACMC-20ms0y; AC1O46MZ; SCHEMBL1764684; CTK0F6605; (aminophenylmethyl)phosphinic acid; DTXSID00422960; JLTNHFQJNQZJTC-UHFFFAOYSA-N
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H8NO2P
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| Canonical SMILES |
C1=CC=C(C=C1)C(=N)P(O)O
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| InChI |
1S/C7H8NO2P/c8-7(11(9)10)6-4-2-1-3-5-6/h1-5,8-10H
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| InChIKey |
HYRMSZQUBBPTOQ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Aminopeptidase N (ANPEP) | Target Info | Inhibitor | [1] |
| BioCyc | Glutathione-mediated detoxification | |||
| KEGG Pathway | Glutathione metabolism | |||
| Metabolic pathways | ||||
| Renin-angiotensin system | ||||
| Hematopoietic cell lineage | ||||
| Pathwhiz Pathway | Glutathione Metabolism | |||
| Pathway Interaction Database | C-MYB transcription factor network | |||
| Reactome | Metabolism of Angiotensinogen to Angiotensins | |||
| WikiPathways | Metabolism of Angiotensinogen to Angiotensins | |||
| Cardiac Progenitor Differentiation | ||||
| miR-targeted genes in squamous cell - TarBase | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| Glutathione metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design of the first highly potent and selective aminopeptidase N (EC 3.4.11.2) inhibitor. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1511-6. | |||
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