Drug Information
Drug General Information | Top | |||
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Drug ID |
D04SHY
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Former ID |
DNC009821
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Drug Name |
Rac-4'-(1-Imidazol-1-yl-propyl)-biphenyl-3,5-diol
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Synonyms |
CHEMBL565098; BDBM50295626
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C18H18N2O2
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Canonical SMILES |
CCC(C1=CC=C(C=C1)C2=CC(=CC(=C2)O)O)N3C=CN=C3
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InChI |
1S/C18H18N2O2/c1-2-18(20-8-7-19-12-20)14-5-3-13(4-6-14)15-9-16(21)11-17(22)10-15/h3-12,18,21-22H,2H2,1H3
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InChIKey |
VBHJJDVRMJRXQC-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Steroid 17-alpha-monooxygenase (S17AH) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Androgen biosynthesis | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Ovarian steroidogenesis | ||||
Prolactin signaling pathway | ||||
Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
Steroidogenesis | ||||
Reactome | Androgen biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | |||
Steroid Biosynthesis | ||||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Glucocorticoid & Mineralcorticoid Metabolism | ||||
Prostate Cancer | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
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REF 1 | Novel CYP17 inhibitors: synthesis, biological evaluation, structure-activity relationships and modelling of methoxy- and hydroxy-substituted methyl... Eur J Med Chem. 2009 Jul;44(7):2765-75. |
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