Drug Information
Drug General Information | Top | |||
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Drug ID |
D05GWI
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Former ID |
DNC007106
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Drug Name |
NSC-106547
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Synonyms |
1,4-Dimethoxyanthracene; 13076-29-4; Anthracene, 1,4-dimethoxy-; NSC-106547; MLS002703923; CHEMBL223575; YCTBFSAWJWMRGO-UHFFFAOYSA-N; NSC106547; NSC 106547; Anthracene,4-dimethoxy-; AC1L34PW; Anthracene,1,4-dimethoxy-; SCHEMBL1061836; DTXSID6065343; CTK4B6912; ZINC1697899; BDBM50195861; SMR001570635; ST50825870
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H14O2
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Canonical SMILES |
COC1=CC=C(C2=CC3=CC=CC=C3C=C12)OC
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InChI |
1S/C16H14O2/c1-17-15-7-8-16(18-2)14-10-12-6-4-3-5-11(12)9-13(14)15/h3-10H,1-2H3
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InChIKey |
YCTBFSAWJWMRGO-UHFFFAOYSA-N
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CAS Number |
CAS 13076-29-4
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Quinone reductase 1 (NQO1) | Target Info | Inhibitor | [1] |
KEGG Pathway | Ubiquinone and other terpenoid-quinone biosynthesis | |||
NetPath Pathway | TCR Signaling Pathway | |||
Pathwhiz Pathway | Vitamin K Metabolism | |||
Pathway Interaction Database | Validated transcriptional targets of TAp63 isoforms | |||
WikiPathways | Estrogen metabolism | |||
Oxidative Stress | ||||
Transcriptional activation by NRF2 | ||||
NRF2 pathway | ||||
Nuclear Receptors Meta-Pathway | ||||
Aryl Hydrocarbon Receptor Pathway | ||||
Apoptosis-related network due to altered Notch3 in ovarian cancer | ||||
Metabolism of amino acids and derivatives | ||||
Aryl Hydrocarbon Receptor | ||||
Dopamine metabolism | ||||
Arylhydrocarbon receptor (AhR) signaling pathway |
References | Top | |||
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REF 1 | In silico identification and biochemical characterization of novel inhibitors of NQO1. Bioorg Med Chem Lett. 2006 Dec 15;16(24):6246-54. |
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