Drug Information
Drug General Information | Top | |||
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Drug ID |
D05HGL
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Former ID |
DIB001912
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Drug Name |
GW-695634
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Synonyms |
GW-5634; GW-5634 Na salt; GW-5634 sodium salt; GW-678248; GW-8248; GW-8635; Non-nucleoside reverse transcriptase inhibitor (hiv infection), GlaxoSmithKline; 678248; 695634
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Indication | Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 279.3] | Phase 1 | [1] | |
Company |
GlaxoSmithKline plc
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Structure |
Download2D MOL |
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Formula |
C26H21Cl2N3O6S
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Canonical SMILES |
CCC(=O)NS(=O)(=O)C1=CC(=C(C=C1)NC(=O)COC2=C(C=C(C=C2)Cl)C(=O)C3=CC(=CC(=C3)C#N)Cl)C
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InChI |
1S/C26H21Cl2N3O6S/c1-3-24(32)31-38(35,36)20-5-6-22(15(2)8-20)30-25(33)14-37-23-7-4-18(27)12-21(23)26(34)17-9-16(13-29)10-19(28)11-17/h4-12H,3,14H2,1-2H3,(H,30,33)(H,31,32)
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InChIKey |
GAQZNFUDILDDDI-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Inhibitor | [2] |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT00090077) Monotherapy Versus Placebo Over 7 Days-Non-Nucleoside Reverse Transcriptase Inhibitor-Experienced HIV1 Infected Adults. U.S. National Institutes of Health. | |||
REF 2 | Next-generation HIV-1 non-nucleoside reverse transcriptase inhibitors. Curr Opin Investig Drugs. 2006 Feb;7(2):128-35. |
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