Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05NTO
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| Former ID |
DNC013419
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| Drug Name |
6'-Iodononivamide
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| Synonyms |
859171-97-4; CHEMBL177809; Tocris-1975; NCGC00025334-01; AC1NP3A0; CTK8E7732; DTXSID70408796; MolPort-003-983-501; CHEBI:107654; HMS3268B17; ZINC8036052; MFCD09878233; BN0036; BDBM50170053; AKOS024456886; RT-010669; N-(4-hydroxy-2-iodo-5-methoxybenzyl)nonanamide; N-(2-Iodo-4-hydroxy-5-methoxybenzyl)nonanamide; 6-Iodonordihydrocapsaicin, > SR-01000597523; SR-01000597523-1; BRD-K49236613-001-01-5; Nonanoic acid 4-hydroxy-2-iodo-5-methoxy-benzylamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C17H26INO3
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| Canonical SMILES |
CCCCCCCCC(=O)NCC1=CC(=C(C=C1I)O)OC
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| InChI |
1S/C17H26INO3/c1-3-4-5-6-7-8-9-17(21)19-12-13-10-16(22-2)15(20)11-14(13)18/h10-11,20H,3-9,12H2,1-2H3,(H,19,21)
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| InChIKey |
AAORACFZMYMFCG-UHFFFAOYSA-N
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| CAS Number |
CAS 859171-97-4
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:107654
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Halogenation of 4-hydroxy/amino-3-methoxyphenyl acetamide TRPV1 agonists showed enhanced antagonism to capsaicin. Bioorg Med Chem. 2010 Nov 15;18(22):8092-105. | |||
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