Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05UGJ
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| Former ID |
DCL000017
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| Drug Name |
XL844
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| Synonyms |
SCHEMBL14517914; XL-844
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Discontinued in Phase 1 | [1] | |
| Therapeutic Class |
Anticancer Agents
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| Company |
Exelixis
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| Structure |
 |
Download2D MOL |
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| Formula |
C14H17N5O2
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| Canonical SMILES |
C1=CC=C(C(=C1)NC(=O)NC2=NC=CN=C2)OCCCN
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| InChI |
1S/C14H17N5O2/c15-6-3-9-21-12-5-2-1-4-11(12)18-14(20)19-13-10-16-7-8-17-13/h1-2,4-5,7-8,10H,3,6,9,15H2,(H2,17,18,19,20)
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| InChIKey |
UVSSZSQSZGKMAL-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00234481) Safety Study of XL844 in Subjects With Chronic Lymphocytic Leukemia. U.S. National Institutes of Health. | |||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | |||
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