Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05YIK
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| Former ID |
DNC013552
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| Drug Name |
(1-hydroxy-1-phosphono-heptyl)-phosphonic acid
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| Synonyms |
(1-Hydroxyheptane-1,1-Diyl)bis(Phosphonic Acid); CHEMBL55264; Phosphonic acid, (1-hydroxyheptylidene)bis-; (1-hydroxy-1-phosphonoheptyl)phosphonic acid; bisphosphonate, 10; AC1NQOTY; SCHEMBL10686529; BDBM25298; 1-Hydroxyheptylidenebisphosphonic acid; AKOS028110532; DB06830; 56375-74-7; 1-hydroxy-1-phosphonoheptylphosphonic acid; (1-hydroxy-1-phosphono-heptyl)phosphonic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H18O7P2
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| Canonical SMILES |
CCCCCCC(O)(P(=O)(O)O)P(=O)(O)O
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| InChI |
1S/C7H18O7P2/c1-2-3-4-5-6-7(8,15(9,10)11)16(12,13)14/h8H,2-6H2,1H3,(H2,9,10,11)(H2,12,13,14)
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| InChIKey |
IJEGNOYPWRBKAE-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Geranyltranstransferase (FDPS) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) | |||
| Superpathway of cholesterol biosynthesis | ||||
| Trans, trans-farnesyl diphosphate biosynthesis | ||||
| Geranylgeranyldiphosphate biosynthesis | ||||
| KEGG Pathway | Terpenoid backbone biosynthesis | |||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Cholesterol biosynthesis | |||
| Pathwhiz Pathway | Steroid Biosynthesis | |||
| Reactome | Cholesterol biosynthesis | |||
| Activation of gene expression by SREBF (SREBP) | ||||
| WikiPathways | Activation of Gene Expression by SREBP (SREBF) | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl... Bioorg Med Chem. 2008 Mar 15;16(6):3283-90. | |||
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