Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D05YUI
|
|||
Former ID |
DIB000968
|
|||
Drug Name |
Ex vivo adenosine deaminase-transduced hematopoietic stem cell therapy
|
|||
Synonyms |
Adenosine deaminase-transduced hematopoietic stem cell therapy; Ex vivo adenosine deaminase-transduced hematopoietic stem cell therapy (ADA-SCID)
Click to Show/Hide
|
|||
Indication | Immunodeficiency [ICD-11: 4A00-4A85; ICD-9: 279.3] | Phase 1/2 | [1] | |
Company |
San Raffaele Telethon Institute for Gene Therapy
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Adenosine deaminase (ADA) | Target Info | Modulator | [2] |
BioCyc | Purine nucleotides degradation | |||
Purine deoxyribonucleosides degradation | ||||
Purine ribonucleosides degradation to ribose-1-phosphate | ||||
Adenosine nucleotides degradation | ||||
Superpathway of purine nucleotide salvage | ||||
Adenine and adenosine salvage III | ||||
KEGG Pathway | Purine metabolism | |||
Metabolic pathways | ||||
Primary immunodeficiency | ||||
NetPath Pathway | TCR Signaling Pathway | |||
IL2 Signaling Pathway | ||||
Panther Pathway | Adenine and hypoxanthine salvage pathway | |||
Pathwhiz Pathway | Purine Metabolism | |||
Pathway Interaction Database | p73 transcription factor network | |||
C-MYB transcription factor network | ||||
Validated transcriptional targets of deltaNp63 isoforms | ||||
Validated transcriptional targets of TAp63 isoforms | ||||
Reactome | Purine salvage | |||
WikiPathways | Metabolism of nucleotides |
References | Top | |||
---|---|---|---|---|
REF 1 | Clinical pipeline report, company report or official report of GlaxoSmithKline. | |||
REF 2 | Clinical pipeline report, company report or official report of GlaxoSmithKline. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.