Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06HKB
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| Former ID |
DIB011572
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| Drug Name |
Lodenosine
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| Synonyms |
FddA; FddI; F-ddN; Fdd analogs, NIH/US Bioscience
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| Drug Type |
Small molecular drug
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| Indication | Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 279.3] | Discontinued in Phase 2 | [1] | |
| Company |
National Cancer Institute
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| Structure |
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Download2D MOL |
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| Formula |
C10H12FN5O2
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| Canonical SMILES |
C1C(OC(C1F)N2C=NC3=C(N=CN=C32)N)CO
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| InChI |
1S/C10H12FN5O2/c11-6-1-5(2-17)18-10(6)16-4-15-7-8(12)13-3-14-9(7)16/h3-6,10,17H,1-2H2,(H2,12,13,14)/t5-,6-,10+/m0/s1
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| InChIKey |
KBEMFSMODRNJHE-JFWOZONXSA-N
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| CAS Number |
CAS 110143-10-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005453) | |||
| REF 2 | 2 ,3 -Dialdehyde of ATP, ADP, and adenosine inhibit HIV-1 reverse transcriptase and HIV-1 replication. Curr HIV Res. 2014;12(5):347-58. | |||
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