Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D06SAT
|
|||
Former ID |
DIB002839
|
|||
Drug Name |
HZ-166
|
|||
Synonyms |
Benzodiazepine derivatives (neuropathic pain); Benzodiazepine derivatives (neuropathic pain), Addiction Therapeutix
Click to Show/Hide
|
|||
Indication | Neuropathic pain [ICD-11: 8E43.0] | Investigative | [1] | |
Company |
University of Wisconsin-Milwaukee
|
|||
Structure |
Download2D MOL |
|||
Formula |
C21H16N4O2
|
|||
Canonical SMILES |
CCOC(=O)C1=C2CN=C(C3=C(N2C=N1)C=CC(=C3)C#C)C4=CC=CC=N4
|
|||
InChI |
1S/C21H16N4O2/c1-3-14-8-9-17-15(11-14)19(16-7-5-6-10-22-16)23-12-18-20(21(26)27-4-2)24-13-25(17)18/h1,5-11,13H,4,12H2,2H3
|
|||
InChIKey |
ZSEDMNMFODMQRD-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | GABA(A) receptor gamma-3 (GABRG3) | Target Info | Modulator | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Retrograde endocannabinoid signaling | ||||
GABAergic synapse | ||||
Morphine addiction | ||||
Nicotine addiction | ||||
Reactome | Ligand-gated ion channel transport | |||
GABA A receptor activation | ||||
WikiPathways | SIDS Susceptibility Pathways | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Iron uptake and transport |
References | Top | |||
---|---|---|---|---|
REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415). |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.