Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07AVV
|
|||
| Drug Name |
Ac-YVAD-cmk
|
|||
| Drug Type |
Peptide
|
|||
| Indication | Allergic contact dermatitis [ICD-11: EK00] | Patented | [1] | |
| Irritant contact dermatitis [ICD-11: EK02; ICD-10: L24, L24.8] | Patented | [1] | ||
| Photocontact dermatitis [ICD-11: EK20; ICD-10: L56.2] | Patented | [1] | ||
| Company |
UNIVERSITY OF COPENHAGEN
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Caspase-1 (CASP1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Caspase-1 (CASP1) | Target's Patent Info | [1] | |
| KEGG Pathway | NOD-like receptor signaling pathway | |||
| Cytosolic DNA-sensing pathway | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Salmonella infection | ||||
| Pertussis | ||||
| Legionellosis | ||||
| Influenza A | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | IL1-mediated signaling events | |||
| Direct p53 effectors | ||||
| IFN-gamma pathway | ||||
| Cellular roles of Anthrax toxin | ||||
| Reactome | NOD1/2 Signaling Pathway | |||
| Interleukin-1 processing | ||||
| The NLRP3 inflammasome | ||||
| WikiPathways | MAPK Signaling Pathway | |||
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | ||||
| Apoptosis | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Parkin-Ubiquitin Proteasomal System pathway | ||||
| Interleukin-1 processing | ||||
| Apoptosis Modulation and Signaling | ||||
| NOD pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Caspase inhibitors: a review of recently patented compounds (2013-2015).Expert Opin Ther Pat. 2018 Jan;28(1):47-59. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.