Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07BFF
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| Former ID |
DNC006241
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| Drug Name |
8-methyl-2-morpholino-7-phenyl-4H-chromen-4-one
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| Synonyms |
CHEMBL95782
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H19NO3
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| Canonical SMILES |
CC1=C(C=CC2=C1OC(=CC2=O)N3CCOCC3)C4=CC=CC=C4
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| InChI |
1S/C20H19NO3/c1-14-16(15-5-3-2-4-6-15)7-8-17-18(22)13-19(24-20(14)17)21-9-11-23-12-10-21/h2-8,13H,9-12H2,1H3
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| InChIKey |
ZMYPEBFYGCAKQT-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3A (PDE3A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Purine metabolism | |||
| cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| WikiPathways | miR-targeted genes in muscle cell - TarBase | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity. Bioorg Med Chem Lett. 2006 Feb 15;16(4):969-73. | |||
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