Drug Information
Drug General Information | Top | |||
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Drug ID |
D07EBW
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Drug Name |
PMID27724045-Compound-17
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Drug Type |
Small molecular drug
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Company |
Janssen Pharmaceutica
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Structure |
Download2D MOL |
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Formula |
C19H16ClF3N6O
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Canonical SMILES |
CCC1CN2C(=NN=C2C(=O)N1CC3=C(C(=CC=C3)C(F)(F)F)Cl)C4=NC=CN=C4
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InChI |
1S/C19H16ClF3N6O/c1-2-12-10-29-16(14-8-24-6-7-25-14)26-27-17(29)18(30)28(12)9-11-4-3-5-13(15(11)20)19(21,22)23/h3-8,12H,2,9-10H2,1H3/t12-/m0/s1
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InChIKey |
XOUUTQMOXWSZSL-LBPRGKRZSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | P2X purinoceptor 7 (P2RX7) | Target Info | Antagonist | [1] |
Target's Patent Info | P2X purinoceptor 7 (P2RX7) | Target's Patent Info | [1] | |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Reactome | The NLRP3 inflammasome | |||
WikiPathways | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways |
References | Top | |||
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REF 1 | P2X7 receptor antagonists: a patent review (2010-2015).Expert Opin Ther Pat. 2017 Mar;27(3):257-267. |
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