Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07EUB
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| Drug Name |
Imidazo[5,1-c]pyrido[2,3-e][1,2,4]triazine derivative 3
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| Synonyms |
PMID27321640-Compound-25
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| Drug Type |
Small molecular drug
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| Company |
STANGE, Hans LANGEN, Barbara EGERLAND, Ute HOEFGEN, Norbert PRIEBS, Martina MALAMAS, Michael, S. ERDEI, James, Joseph NI, Yike BIOTIE THERAPIES GMBH WYETH
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| Structure |
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Download2D MOL |
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| Formula |
C17H14FN5O2
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| Canonical SMILES |
CC1=C2N=NC3=C(N2C(=N1)C4=C(C=CC(=C4)OC)F)N=C(C=C3)OC
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| InChI |
1S/C17H14FN5O2/c1-9-15-22-21-13-6-7-14(25-3)20-17(13)23(15)16(19-9)11-8-10(24-2)4-5-12(11)18/h4-8H,1-3H3
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| InChIKey |
HLUWBLAYMFWHOF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 10A (PDE10) | Target Info | Inhibitor | [1] |
| Phosphodiesterase 2A (PDE2A) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | Phosphodiesterase 10A (PDE10) | Target's Patent Info | [1] | |
| Phosphodiesterase 2A (PDE2A) | Target's Patent Info | [1] | ||
| KEGG Pathway | Purine metabolism | |||
| Morphine addiction | ||||
| cGMP-PKG signaling pathway | ||||
| NetPath Pathway | TSH Signaling Pathway | |||
| Pathwhiz Pathway | Purine Metabolism | |||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Towards selective phosphodiesterase 2A (PDE2A) inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2016 Aug;26(8):933-46. | |||
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